中华卫生杀虫药械

目的 通过分析2013—2019年河北省肾综合征出血热(HFRS)监测资料，描述其流行特征和变化趋势，为疾病防控提供依据。方法 采用描述性流行病学方法对HFRS监测资料进行统计分析。结果 河北省2013—2019年HFRS平均发病率为0.945 2/10万，平均病死率为0.286 4%。2013—2019年发病率整体呈现下降趋势，高发病率地区主要集中在秦皇岛市(2 170例，10.093 2/10万)、唐山市(1 998例，3.677 4/10万)和承德市(234例，0.939 0/10万);全年各月均有病例报告，呈现出“双峰型”分布，3—5月为全年发病最高峰；发病以青壮年及中老年男性为主，职业分布以农民居多；时空分布结果显示，河北省HFRS自然疫源地呈现由秦皇岛市和唐山市向承德市扩散的趋势；鼠带毒率与地区人群发病率呈正相关(r=0.721,P﹤0.001)。结论 河北省HFRS疫情整体呈现下降并趋于平稳，季节分布和地理分布不均，对高发地区需加强监测，强化疫苗接种意识，落实防鼠灭鼠工作。

Objective To analyze the surveillance data of hemorrhagic fever with renal syndrome(HFRS) in Hebei Province from 2013 to 2019,providing evidence for HFRS prevention and control.Methods The surveillance data of HFRS collected were analyzed by descriptive epidemiology.Results The overall incidence of HFRS in Hebei Province from 2013 to 2019 was 0.945 2 per 100 000 of the population, and the overall fatality was 0.286 4%.The incidence showed a downward trend from 2013 to 2019.The cases were found mostly in Qinhuangdao City(2 170 cases, 10.093 2 per 100 000),Tangshan City(1 998 cases, 3.677 4 per 100 000) and Chengde City(234 cases, 0.939 0 per 100 000).Cases were reported in each month of the years, presenting a “bimodal” distribution, and the peak of the annual incidence was from March to May.Young and middle-aged males were the main victims of the disease, and farmers took bigger proportion among occupations.The temporal and spatial distribution showed that the natural foci of HFRS in Hebei Province were spreading from Qinhuangdao and Tangshan to Chengde.There was a positive correlation between the virus carrying rate in rodents and the morbidity in human(r=0.721,P﹤0.001).Conclusion The HFRS epidemic situation in Hebei Province showed a decreasing trend and tended to be stable as a whole, with uneven seasonal and geographical distribution.It is necessary to strengthen the monitoring in high-incidence areas, promote the awareness of vaccination, and carry out rodenticide-control work.