中华卫生杀虫药械

目的 了解咸阳市城区白纹伊蚊对常用杀虫剂的抗药性水平，为合理选择和使用卫生杀虫剂，指导白纹伊蚊的控制提供科学依据。方法 采用WHO推荐的成蚊接触桶法与幼虫浸渍法测定白纹伊蚊对常用杀虫剂的抗药性，使用SPSS 26.0软件计算半数致死浓度(LC₅₀)以及毒力回归方程。结果 2016年咸阳市白纹伊蚊成蚊用高效氯氰菊酯、溴氰菊酯和氯菊酯处理的死亡率分别为98.90%、98.00%、95.92%,幼虫对高效氯氰菊酯、氯菊酯、双硫磷、溴氰菊酯的抗性倍数分别为2.48、5.59、1.58、2.94;2023年咸阳市白纹伊蚊成蚊用马拉硫磷、氯氰菊酯、溴氰菊酯、高效氯氰菊酯处理的死亡率分别为97.89%、 57.14%、47.87%、74.44%,幼虫对高效氯氰菊酯、溴氰菊酯、顺式氯氰菊酯、双硫磷的抗性倍数分别为37.86、332.26、8.77、6.71。结论 2023年咸阳市白纹伊蚊对常用杀虫剂抗性较2016年总体有所上升，溴氰菊酯上升最高，对高效氯氰菊酯和溴氰菊酯为高水平抗性，对顺式氯氰菊酯和双硫磷为低水平抗性；建议合理轮换使用杀虫剂，延缓白纹伊蚊抗药性的发展。

Objective To understand the resistance level of Aedes albopictus to commonly used insecticides in the urban area of Xianyang, so as to provide scientific basis for rational selection and use of insecticides and guiding the control of Ae. albopictus. Methods The adult mosquito contact bucket method and larval immersion method recommended by WHO were used to determine the resistance of Ae. albopictus to commonly used insecticides. SPSS 26.0 software was used to calculate the median lethal concentration(LC₅₀) of insecticides against mosquitoes and the toxicity regression equation. Results In 2016, the mortality rates of adult mosquitoes treated with beta-cypermethrin, deltamethrin and permethrin were 98.90%, 98.00%, and 95.92%, respectively. The resistance ratios of Ae. albopictus in Xianyang to beta-cypermethrin, permethrin, temephos, and deltamethrin, were 5.59, 2.48, 2.94, and 1.58, respectively. In 2023, the mortality rates of adult mosquitoes treated with malathion, cypermethrin, deltamethrin, and beta-cypermethrin were 97.89%, 57.14%, 47.87% and 74.44%, respectively. The resistance ratios of Ae. albopictus to beta-cypermethrin, deltamethrin, alpha-cypermethrin, and temephos were 37.86, 332.26, 8.77, and 6.71, respectively. Conclusion The resistance of Ae. albopictus to common insecticides in Xianyang had increased in 2023 compared with those of 2016, and the resistance level to deltamethrin was the highest. Ae. albopictus showed a high-level resistance to beta-cypermethrin and deltamethrin, and a low-level resistance to alpha-cypermethrin and temephos. It was suggested that insecticides should be used rationally and alternately, so as to delay the development of resistance.